Jeanne A M C Dirks

Background: Chlamydia trachomatis (CT) has 4-10 plasmids per bacterium that contain virulence-factors for survival. CT can increase plasmid numbers when stressed, as occurs in clinical trachoma samples. No studies have investigated plasmid copy numbers in clinical samples. Most diagnostic CT assays target the plasmid to increase their sensitivity, but some have other targets. We investigated plasmid copy numbers in urogenital CT samples to assess...